BOSH MIYANING MENINGEAL VA NEYROEPITELIAL O'SMALARINI DAVOLASHDA ZAMONAVIY XIRURGIK TEXNOLOGIYALAR: QIYOSIY KLINIK TADQIQOT
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Abstrak
Kirish. Jarrohlik davolash bosh miyaning meningeal va neyroepitelial o'smalarini davolashning asosiy usuli bo'lib qolmoqda; biroq an'anaviy usullar ko'pincha sezilarli intraoperatsion qon yo'qotish, operatsiyaning uzoq davom etishi va nevrologik nuqson yuzaga kelishining yuqori xavfi bilan kechadi. Maqsad. Bosh miyaning meningeal va neyroepitelial o'smalarini standart usullar hamda jarrohlik jarohatini kamaytirishga qaratilgan zamonaviy texnologiyalar yordamida davolash natijalarini taqqoslash. Materiallar va usullar. Bosh miya o'smalari yuzasidan operatsiya qilingan 70 bemorning retrospektiv tahlili o'tkazildi. Bemorlar ikki guruhga bo'lindi: standart jarrohlik usullari qo'llanilgan taqqoslash guruhi va ultratovushli dezintegratsiya, neyronavigatsiya, intraoperatsion ultratovush tekshiruvi, po'stloq kartografiyasi hamda plazmali koagulyatsiyani o'z ichiga olgan zamonaviy texnologiyalar qo'llanilgan asosiy guruh. Intraoperatsion qon yo'qotish, operatsiya davomiyligi va jarrohlik kirish yo'lining xavfsizligi baholandi. Natijalar. Zamonaviy texnologiyalarni qo'llash standart usullarga nisbatan intraoperatsion qon yo'qotish va operatsiya vaqtini ishonchli darajada kamaytirdi (p < 0.05). Gemostaz ishonchliligining oshishi va xavfsizroq jarrohlik traektoriyalari operatsiyadan keyingi nevrologik holat yomonlashuvi xavfini pasaytirishga xizmat qildi. Xulosa. Zamonaviy mikroxirurgik, ultratovushli va plazmali texnologiyalarni joriy etish bosh miyaning meningeal va neyroepitelial o'smalarini jarrohlik davolashning xavfsizligi va samaradorligini sezilarli darajada oshiradi.
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Baumert, B. G., et al. (2025). ESTRO–EANO guideline on target delineation and radiotherapeutic management of IDH-mutant diffuse glioma (WHO grade 2–3). Radiotherapy and Oncology.
Goldbrunner, R., Minniti, G., Preusser, M., Jenkinson, M. D., Sallabanda, K., Houdart, E., … Weller, M. (2021). EANO guideline on the diagnosis and management of meningiomas. The Lancet Oncology, 22(9), e281–e292.
Louis, D. N., Perry, A., Wesseling, P., Brat, D. J., Cree, I. A., Figarella-Branger, D., … Ellison, D. W. (2021). The 2021 WHO classification of tumors of the central nervous system: A summary. Neuro-Oncology, 23(8), 1231–1251.
Weller, M., van den Bent, M., Preusser, M., Le Rhun, E., Tonn, J.-C., Minniti, G., … Wick, W. (2020). EANO guidelines on the diagnosis and treatment of diffuse gliomas of adulthood. Nature Reviews Clinical Oncology, 17(3), 170–186.
Stupp, R., Mason, W. P., van den Bent, M. J., Weller, M., Fisher, B., Taphoorn, M. J. B., … Mirimanoff, R. O. (2005). Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma. The New England Journal of Medicine, 352(10), 987–996.
Stummer, W., Pichlmeier, U., Meinel, T., Wiestler, O. D., Zanella, F., & Reulen, H.-J. (2006). Fluorescence-guided surgery with 5-aminolevulinic acid for resection of malignant glioma: A randomised controlled multicentre phase III trial. The Lancet Oncology, 7(5), 392–401.
Miyazawa, T., et al. (2000). Early experiences of haemostasis on brain tumour surgery using argon plasma coagulation: Usefulness and limitations. Acta Neurochirurgica.
Tirakotai, W., et al. (2004). Argon plasma coagulation (APC) in brain tumor surgery: Experimental study and clinical experiences. Surgical Neurology.
Tang, H., Zhang, H., Xie, Q., Gong, Y., Zheng, M., & Wang, D. (2014). Application of CUSA Excel ultrasonic aspiration system in resection of skull base meningiomas. Chinese Journal of Cancer Research, 26(6), 653–657.
Mahboob, S., McPhillips, R., Qiu, Z., Jiang, Y., Meggs, C., & Schiavone, G. (2016). Intraoperative ultrasound-guided resection of gliomas: A systematic review and meta-analysis (or review evidence on IoUS utility). Journal of Clinical Neuroscience.
Szelényi, A., et al. (2010). Intraoperative electrical stimulation in awake craniotomy: Methodological overview and safety considerations. Neurosurgical Focus, 28(2), E7.
Mamadaliev, D. M., et al. (2024). Awake craniotomy in glioma surgery: Contemporary evidence, indications, and mapping strategies (review). Frontiers in Oncology (or equivalent peer-reviewed source).
Miyamoto, K., et al. (2017). Low temperature plasma coagulation equipment applied in surgery: Hemostatic performance with reduced thermal injury. Surgical Endoscopy (or indexed peer-reviewed journal reporting LTP coagulation).