VINKRISTIN NEYROPATIYASI

Maqola yon paneli

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Nashr qilingan: 2025-05-05
DOI: https://doi.org/10.66073/researchfocus.v4i4.1594
Kalit so‘zlar:
vinkristin neyropatiyasi, kimyoterapiya, neyrotoksiklik, sensor polineyropatiya, nojo'ya ta'sirlar, onkologiya, nevrologik nazorat

Maqolaning asosiy mazmuni

Gulyamova Durdona Nasriddinovna
Toshkent vrachlar malakasini oshirish instituti, Bolalar nevrologiyasi kafedrasi
Abduraxmonova Nigora
Bolalar gematologiyasi, onkologiyasi va klinik immunologiyasi markazi
Matyakubova Xonzoda Bekturdiyevna

Abstrak

Vinkristin neyropatiyasi vinkristin qo'llaniladigan kimyoterapiyaning eng keng tarqalgan va eng muhim asoratlaridan biridir. U asosan periferik sensor va motor buzilishlar ko'rinishida namoyon bo'lib, bemorlarning hayot sifatiga sezilarli ta'sir ko'rsatadi va davolashni davom ettirishni cheklashi mumkin. Maqolada vinkristin neyropatiyasining klinik ko'rinishlari, patogenetik mexanizmlari, xavf omillari, tashxislash usullari hamda profilaktika va davolash yondashuvlari ko'rib chiqilgan. Samarali neyroprotektiv strategiyalarni ishlab chiqish va vinkristin bilan davolanayotgan bemorlarni olib borishni yaxshilashga qaratilgan keyingi tadqiqotlar zarurligi qayd etilgan.

Maqola tafsilotlari

Nashr

Jild 4 Nomeri 4 (2025): Research Focus International Scientific Journal. 4-tom, 4-son (2025)

Bo'lim

14.00.00 – Tibbiyot fanlari
Creative Commons litsenziyasi

Ushbu asar Creative Commons Attribution 4.0 International litsenziyasi asosida litsenziyalangan.

Qanday iqtibos keltirish kerak

VINKRISTIN NEYROPATIYASI. (2025). Research Focus International Scientific Journal, 4(4), 278-280. https://doi.org/10.66073/researchfocus.v4i4.1594

Adabiyotlar

Verstappen, C. C. P., Heimans, J. J., Hoekman, K., Postma, T. J. (2003). Neurotoxic complications of chemotherapy in patients with cancer: clinical signs and optimal management. Drugs, 63(15), 1549–1563.

Cavaletti, G., Marmiroli, P. (2010). Chemotherapy-induced peripheral neurotoxicity. Current Opinion in Neurology, 23(5), 566–575.

Gomber, S., Dewan, P., Chhonker, D. (2010). Vincristine induced neurotoxicity: Diagnosis and management. Indian Journal of Pediatrics, 77(6), 643–646.

Park, S. B., Goldstein, D., Krishnan, A. V., Lin, C. S. Y., Friedlander, M. L., Kiernan, M. C. (2013). Chemotherapy-induced peripheral neurotoxicity: a critical analysis. CA: A Cancer Journal for Clinicians, 63(6), 419–437.

Verstappen, C. C. P., Postma, T. J., Hoekman, K., Heimans, J. J. (2005). Peripheral neuropathy due to chemotherapy: A review on the pathophysiology and therapeutic options. European Journal of Cancer, 41(3), 437–445.

Starobova, H., Vetter, I. (2017). Pathophysiology of chemotherapy-induced peripheral neuropathy. Frontiers in Molecular Neuroscience, 10, 174.

Windebank, A. J., Grisold, W. (2008). Chemotherapy-induced neuropathy. Journal of the Peripheral Nervous System, 13(1), 27–46.

Grisold, W., Cavaletti, G., Windebank, A. J. (2012). Peripheral neuropathies from chemotherapeutics and targeted agents: diagnosis, treatment, and prevention. Neuro-Oncology, 14(suppl_4), iv45–iv54.