BIR YOSHGACHA BO‘LGAN BOLALARDA MIOKARDNING PATOMORFOLOGIK O‘ZGARISHLARI

Maqola yon paneli

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Nashr qilingan: 2026-04-05
DOI: https://doi.org/10.66073/researchfocus.v5i3.2361
Kalit so‘zlar:
miokard, patomorfologik o‘zgarishlar, kardiomiyotsit, perinatal gipoksiya interstitsial shish, fibroz, neonatal kardiopatologiya

Maqolaning asosiy mazmuni

Urunova M.A
v.v.b. dotsent ZARMED universiteti; Assistant ZARMED universiteti
Ernazarov M.E
v.v.b. dotsent ZARMED universiteti; Assistant ZARMED universiteti

Abstrak

Ushbu maqolada bir yoshgacha bo‘lgan bolalarda miokardning patomorfologik o‘zgarishlari zamonaviy ilmiy adabiyotlar asosida tahlil qilindi. Mavjud tadqiqotlar ko‘rsatishicha, erta ontogenez davrida yurak mushagi gipoksiya, yallig‘lanish va gemodinamik buzilishlarga yuqori sezuvchan bo‘ladi. Adabiyotlar sharhi natijasida perinatal gipoksiya va infeksion omillar ta’sirida kardiomiyotsitlar gipertrofiyasi, interstitsial shish degenerativ-distrofik jarayonlar hamda boshlang‘ich fibroz o‘zgarishlar rivojlanishi qayd etilishi aniqlandi. Tahlillar miokarddagi strukturaviy qayta qurilishlar mikrosirkulyatsiya buzilishi va hujayraviy gipoksiya bilan chambarchas bog‘liqligini ko‘rsatadi. Ushbu ma’lumotlar erta tashxis va profilaktik kuzatuvni takomillashtirish zarurligini asoslaydi.

Maqola tafsilotlari

Nashr

Jild 5 Nomeri 3 (2026): Research Focus xalqaro ilmiy jurnali. 5-tom, 3-son (2026)

Bo'lim

14.00.00 – Tibbiyot fanlari
Creative Commons litsenziyasi

Ushbu asar Creative Commons Attribution 4.0 International litsenziyasi asosida litsenziyalangan.

Qanday iqtibos keltirish kerak

BIR YOSHGACHA BO‘LGAN BOLALARDA MIOKARDNING PATOMORFOLOGIK O‘ZGARISHLARI. (2026). Research Focus International Scientific Journal, 5(3), 145-151. https://doi.org/10.66073/researchfocus.v5i3.2361

Adabiyotlar

Bolli R. Inflammation and cardiac remodeling in neonatal hearts // J Mol Cell Cardiol. — 2014. — Vol.67, P. 11–

Gidding S.S., Allen H.D., Freed M.D. Congenital and Inherited Heart Disease in Children // Circulation. — 2010. — Vol.121, No.

Huang H., Zhang L., Nie C. et al. Pathological changes of myocardium in neonatal respiratory distress syndrome // Pediatr Pathol Mol Med. — 2018. — Vol.37, No.

North K.N., Sinclair D.A. Molecular mechanisms mediating hypoxia–induced cardiac injury in neonates // J Clin Invest. — 2012. — Vol.122, No.

O‘zbekiston Respublikasi Sog‘liqni saqlash vazirligi. Perinatal salomatlikni yaxshilash dasturi 2024–2030 yillar. Tashkilot rasmiy hujjati. — Toshkent, 2024. — 56 b.

Paauw N.D. et al. Neonatal cardiac gipertrofiya: the role of hyperinsulinism — a review of literature // European Journal of Pediatrics. — 2020. — Vol.179. — P.39–

Pathomorphology of the heart in newborn infants with RDS syndrome / International Multidisciplinary Journal for Research & Development. — 2025. — Vol.12, Issue

— P. 494–501. (inlibrary.uz)

Pavlyukova E.N., Kolosova M.V., Neklyudova G.V. Children’s heart and prematurity: a current view of the problem // Kazan Medical Journal. — 2024. — Vol.105, No.

Saryeva O.P., Kulida L.V., Protsenko E.V. Cardiomyopathy in children — clinical, genetic and morphological aspects // I.P. Pavlov Russian Medical Biological Herald. — 2020. — Vol.28 No.

Towbin J.A., Lowe A.M., Colan S.D. et al. Incidence and etiology of pediatric myocarditis // JAMA Cardiol. — 2019. — Vol.4, No.

World Health Organization. Global Pediatric Cardiovascular Health Report. — WHO, 2023. — 84 p. (who.int)

Zhao Q., Xu Y., Dong J. et al. Epidemiology and clinical characteristics of neonatal critical congenital heart disease // World J Pediatr. — 2021. — Vol.17, No.

Мекенбаева Р.Т. Клинические и морфологические изменения в миокарде у умерших новорождённых, перенесших перинатальную гипоксию // Journal of Clinical Medicine of Kazakhstan. — 2013. — Т.3, №