PHLOMOIDES NUDA O‘SIMLIGI TARKIBIDAN AJRATIB OLINGAN AYRIM MODDALARNING TARKIBI VA TUZILISHINI KVANT-KIMYOVIY HISOBLASH METODI YORDAMIDA TAQQOSLASH

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Nashr qilingan: 2025-06-05
DOI: https://doi.org/10.66073/researchfocus.v4i5.1608
Kalit so‘zlar:
Phlomoides nuda, ekdisteron, α-ekdizon, 8-O-asetilgarpagid, lamiid, pinitol, DFT, Gaussian 98, infraqizil spektroskopiya, molekulyar strukturasi, vodorod bog‘lanish, tebranish modlari

Maqolaning asosiy mazmuni

M.M.Mexmonxonov, F.Q. Abdullayeva, D.R.Xaydarova
Namangan State University image/svg+xml

Abstrak

Ushbu ilmiy maqolada Namangan viloyati Yangiqo‘rg‘on tumanida o‘suvchi Phlomoides nuda o‘simligi tarkibidan ajratib olingan biologik faol birikmalar — ekdisteron, α-ekdizon, 8-O-asetilgarpagid, lamiid va pinitol molekulalarining strukturasi DFT/B3LYP/3-21G usuli asosida kvant-kimyoviy hisoblash dasturi Gaussian 98 orqali optimallashtirildi. Ularning infraqizil tebranish (IQ) spektrlari eksperimental va nazariy jihatdan qiyoslab tahlil qilindi. Natijalar shuni ko‘rsatdiki, molekulalarning eksperimental spektrlari nazariy spektral cho‘qqilar bilan yuqori darajada mos keladi. Ayniqsa, deformasion va valent tebranishlarga oid tebranish modlari aniqligi molekulalardagi halqalar soni, C-O, C-H, C- C bog‘larining mavjudligini va tuzilmaning aniqligini tasdiqlaydi. Bu tahlil natijalari ajratilgan moddalarning kimyoviy strukturasi yuqorida keltirilgan formulalar asosida tasdiqlanishiga asos bo‘ldi.

Maqola tafsilotlari

Nashr

Jild 4 Nomeri 5 (2025): Research Focus International Scientific Journal. 4-tom, 5-son (2025)

Bo'lim

02.00.00 – Kimyo fanlari
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Qanday iqtibos keltirish kerak

PHLOMOIDES NUDA O‘SIMLIGI TARKIBIDAN AJRATIB OLINGAN AYRIM MODDALARNING TARKIBI VA TUZILISHINI KVANT-KIMYOVIY HISOBLASH METODI YORDAMIDA TAQQOSLASH. (2025). Research Focus International Scientific Journal, 4(5), 29-35. https://doi.org/10.66073/researchfocus.v4i5.1608

Adabiyotlar

Moench, H. (2023). Phlomoides Systematics and Phytochemistry. Journal of Medicinal Plants Research, 15(2), 115-130.

Gaussian 98 User’s Reference. Gaussian, Inc., Pittsburgh, 2001.

Ikromov, S., & Xudoyberganov, A. (2020). O‘zbekiston florasi. Toshkent: Fan.

Tursunov, M., & Valiev, A. (2019). Biological Activity of Plant-Derived Ecdysteroids. Uzbekistan Journal of Natural Sciences, 8(3), 50-56.

Zhang, L., et al. (2018). Phytochemical Analysis of Ecdysteroids from Plant Extracts. Phytochemistry, 145, 23-34.

Chen, Y., Wang, Z., & Li, H. (2017). Molecular Docking of Plant Ecdysteroids and Their Effects on Human Cells. Molecular Biology Reports, 44(5), 333-340.

Akhmedov, M. (2015). Infrared Spectroscopy in Plant Chemistry Studies. Tashkent: Science and Technology Publishing.

Kurbanov, A., & Mahmudov, H. (2014). Application of Quantum Chemistry in Plant Secondary Metabolites Analysis. Chemica Scripta, 7(1), 23-29.