CLINICAL ASPECTS OF GRAVITATIONAL SURGERY IN THE TREATMENT OF STEROID-DEPENDENT AND STEROID-RESISTANT FORMS OF NONSPECIFIC ULCERATIVE COLITIS

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Published: 2024-01-05
DOI: https://doi.org/10.66073/researchfocus.v2i12.664
Keywords:
Nonspecific ulcerative colitis, steroid-dependent and steroid-resistant forms, plasmapheresis

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Shodmonov A.A
Samarkand State Medical University, Faculty of Dentistry, 1st year student; Scientific supervisor: Abulqosimova Dildora Asrorovna; Samarkand State Medical University, Department of Social and Humanitarian Sciences, assistant
Qurbaniyazov Z.B
Samarkand State Medical University, Faculty of Dentistry, 1st year student; Scientific supervisor: Abulqosimova Dildora Asrorovna; Samarkand State Medical University, Department of Social and Humanitarian Sciences, assistant
Askarov P.O
Samarkand State Medical University, Faculty of Dentistry, 1st year student; Scientific supervisor: Abulqosimova Dildora Asrorovna; Samarkand State Medical University, Department of Social and Humanitarian Sciences, assistant
Rustamov I.M.
Samarkand State Medical University, Faculty of Dentistry, 1st year student; Scientific supervisor: Abulqosimova Dildora Asrorovna; Samarkand State Medical University, Department of Social and Humanitarian Sciences, assistant

Abstract

This paper analyses clinical material based on the results of a comprehensive examination and treatment of 102 patients with a confirmed diagnosis of nonspecific ulcerative colitis. The positive dynamics of general clinical and laboratory indicators and of the endoscopic picture in patients with steroid-dependent and steroid-resistant forms of nonspecific ulcerative colitis, when a course of extracorporeal plasmapheresis procedures was used for their treatment, indicates its effectiveness in relieving exacerbation of the disease. Despite the use of minimal doses of corticosteroids during plasmapheresis sessions, compared with standard therapy, in patients with steroid-dependent and steroid-resistant forms of nonspecific ulcerative colitis remission is achieved more frequently (from 22% to 96%), complications from the long-term intake of corticosteroids are significantly reduced, and the possibility of complete withdrawal of maintenance therapy has been achieved, which ultimately leads to an improvement in the quality of life of this category of patients.

Article Details

Issue

Vol. 2 No. 12 (2023): Research Focus International Scientific Journal. Volume 2, Issue 12 (2023)

Section

14.00.00 – Medical sciences
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This work is licensed under a Creative Commons Attribution 4.0 International License.

How to Cite

CLINICAL ASPECTS OF GRAVITATIONAL SURGERY IN THE TREATMENT OF STEROID-DEPENDENT AND STEROID-RESISTANT FORMS OF NONSPECIFIC ULCERATIVE COLITIS. (2024). Research Focus International Scientific Journal, 2(12), 140-147. https://doi.org/10.66073/researchfocus.v2i12.664

References

Белоусова, E. A. Язвенный колит и 6олезнь Крона / E. A. Белоусова. – Tверь: Tриада, 2012. – 128 с.

Воробьев, F. N. Неспецифические воспалительные заболевания кишечника / F. N. Воробьев, N. Л. Халиф. – М.: Миклом, 2013. – 400 с.

Неспецифический язвенный колит / Ф. N. Комаров [и др.]. – М.: ООО «Мед. информ. агентство», 2018. – 256 с.

Халиф, N. Л. Лече6ная тактика при язвенном колите / N. Л. Халиф // Рос. журн. гастро энтерол., гепатологов и колопроктологов – 2014. – № 3. – С. 58-61.

Michelassi, F. Inflammatory Boyel Disease / F. Michelassi, A. Fichera; еd. J. B. Kirshner. – 5-th ed. – Philadelphia, 2017. – P. 616-626.

Шодмонов А. А., Аскаров П. А., Рустамов И. М. Клиническая эффективность гравитационной хирургии в лечении неспецифического язвенного колита // Том-1. – 2022. – с. 546.