Histomorphological assessment of a drug complex in experimental tuberculosis of calves

Main Article Content

O. A. DJURAEV

Abstract

The article presents the results of histological studies of the internal organs of experimental calves used in experiments to study the effects of a new complex of anti-tuberculosis drugs, Rifizostrep. It has been established that this drug, when used over a long period in animals with experimental tuberculosis, has a sufficiently high bactericidal activity against pathogens of the M. tuberculosis-7880 strain. Along with this, it was found that Rifizostrep has no side effects or negative effects on the body as a whole or on the structure of the internal organs of the experimental calves in particular.

Article Details

How to Cite
DJURAEV, O. A. (2026). Histomorphological assessment of a drug complex in experimental tuberculosis of calves. Research Focus International Scientific Journal, 5(7), 36–38. https://doi.org/10.66073/ReFocus.V5I7.0705
Section
16.00.00 – Veterinary sciences

References

Alimov V.A., Egamberdieva Z.Z. Patologik anatomiyadan qo‘llanma [A manual of pathological anatomy]. Tashkent, Ibn Sino, 1993, 168 p. (in Uzbek)

Antonov B.I. et al. Laboratornye issledovaniya v veterinarii [Laboratory investigations in veterinary medicine]. Moscow, Agropromizdat, 1986, 352 p. (in Russian)

Garifullin Z.R. Proceedings of the jubilee session dedicated to the 80th anniversary of the Central Research Institute of Tuberculosis. Moscow, 2001, pp. 113–114. (in Russian)

Djuraev O.A. Patologoanatomicheskoe vskrytie zhivotnykh i ptits [Pathoanatomical autopsy of animals and birds]. Samarkand, SHUXRAT MENGLIYEV, 2026, 162 p. (in Russian)

Djuraev O.A., Mamadullaev G.Kh., Fayziev U.M. Dengiz cho‘chqachalarida Rifizostrep preparatini sinashning patomorfologik natijalari [Pathomorphological results of testing Rifizostrep in guinea pigs]. O‘zbekiston qishloq va suv xo‘jaligi, 2022, spec. iss. 2, pp. 62–64. (in Uzbek)

Djuraev O.A. Veterinariyada patologoanatomik yorib tekshirish [Pathoanatomical dissection in veterinary medicine]. Samarkand, ARTEX NASHR, 2024, 116 p. (in Uzbek)

Ibodullaev F. Qishloq xo‘jalik hayvonlarining patologik anatomiyasi [Pathological anatomy of farm animals]. Tashkent, O‘zbekiston, 2000, 420 p. (in Uzbek)

Treatment of tuberculosis: guidelines for national programmes. WHO, Geneva, 1998, 77 p.

Mamadullaev G.Kh., Elmurodov B.A., Djuraev O.A., Djurakulov O.K., Fayziev U.M. Rifizostrep — novyy kombinirovannyy preparat protiv mikobakteriy tuberkuleza [Rifizostrep, a new combined preparation against Mycobacterium tuberculosis]. Epizootologiya, immunobiologiya, farmakologiya, sanitariya, Minsk, 2022, no. 2, pp. 52–57. (in Russian)

Rekomendatsii po laboratornoy diagnostike tuberkuleza [Guidelines for the laboratory diagnosis of tuberculosis]. Omsk, 1988, 64 p. (in Russian)

Tuberkulez: opredelenie lekarstvennoy ustoychivosti k osnovnym protivotuberkuleznym preparatam [Tuberculosis: determination of drug resistance to the main anti-tuberculosis drugs]. Problemy tuberkuleza, 2008, no. 4, p. 38. (in Russian)

Tuberkulez selskokhozyaystvennykh zhivotnykh [Tuberculosis of farm animals], ed. V.P. Shishkov, V.P. Urban. Moscow, Agropromizdat, 1991, 246 p. (in Russian)

Hayvonlar tuberkulyozining oldini olish va qarshi kurash: yo‘riqnoma [Prevention and control of animal tuberculosis: instructions]. Tashkent, 1998, 16 p. (in Uzbek)

Yarbaev N., Mirzoev D.M., Khabibov A. Problemy profilaktiki i ozdorovleniya zhivotnovodcheskikh khozyaystv ot tuberkuleza KRS [Problems of prevention and eradication of bovine tuberculosis on livestock farms]. Kishovarz, Dushanbe, 2004, no. 1, pp. 33–36. (in Russian)