ASSESSMENT OF SERUM LEVELS OF GONADOTROPINS AND TESTOSTERONE IN PATIENTS WITH CHRONIC LUNG PATHOLOGY

Main Article Content

Mamatkulova Dilrabo Xamidovna

Abstract

Pubertal development was assessed and serum hormonal status was studied in patients with chronic lung disease (CLD). The study included 140 children with CLD. The results revealed significant differences in the timing of the onset of pubertal changes, the intensity of secondary sexual characteristics (SSC) development, and functional disturbances in the pituitary- gonadal axis, characterized by increased follicle-stimulating hormone (FSH) levels, decreased luteinizing hormone (LH), and decreased testosterone in boys with CLD. In girls with CLD, FSH levels were not significantly elevated at the onset of puberty. LH levels were significantly lower throughout puberty, and estradiol levels were significantly lower in older age groups. Thus, CLD negatively impacts the sexual development of children, necessitating the development of specific practical measures in this area.

Article Details

How to Cite
Xamidovna, M. D. (2026). ASSESSMENT OF SERUM LEVELS OF GONADOTROPINS AND TESTOSTERONE IN PATIENTS WITH CHRONIC LUNG PATHOLOGY. Research Focus International Scientific Journal, 5(5), 206–211. Retrieved from https://refocus.uz/index.php/rf/article/view/2275
Section
14.00.00 – Medical sciences

References

Астафьева Н. Г. Медико-социальная экспертиза подростков с хроническими заболеваниями легких // Российский вестник перинатологии и педиатрии. 2003. №

Богданова А. В. с соавт. Эпидемиологические аспекты хронических болезней мелких бронхов у детей // Вестник современной клинической медицины. 2015. Т. 8, №

Блинова И. М., Ботвиньева В. В. Характеристика двусторонних хронических пневмоний у детей // Материалы 7-го Национального конгресса по болезням органов дыхания: тезисы докладов. Москва, 1997. С. 232.

Бобомуратов Т. А., Маматкулова Д. Х. Болаларда бронх-ўпка касалликларида регионал лимфотроп терапиянинг афзалликлари // Проблемы биологии и медицины. Самарканд 2003. №

Искандарова Ш. Т. Физическое развитие и заболеваемость подростков, проживающих в Ташкенте // Педиатрия. 2003. С. 10–

Mamatkulova Dilrabo Khamidovna, Sharipova Oliya Askarovna. Treatment algorithm for chronic obstructive lung disease // Инновационное развитие науки и образования: Международная научно-практическая конференция. Казахстан, июнь 2020. С. 55–

Прахин Е. И., Грицинская В. Л. Характеристика методов оценки физического развития детей // Педиатрия. 2004. №

Уланова Л. Н. и др. О стандартизации показателей полового созревания детей и подростков // Педиатрия. 1981. №

Bobomuratow T. A., Sharipova O. A., Mamatkulova D. X., Bakhronov Sh. S. Features of sexual development state of the pituitary-gonadal system and measures of secondary prevention in sick children with chronic bronchitis // International Journal of Pharmaceutical Research. 2020. P. 377–381.

Yende S., Waterer G. W., Tolley E. A. et al. Inflammatory markers are associated with ventilator limitation and muscle dysfunction in lung disease in well-functioning elderly subjects // Thorax. 2006. Vol.

Sharipova O. A., Bakhronov Sh. S., Rustamova G. R. Comparative evaluation of effectiveness of secondary stage prophylaxis in patients with chronic bronchitis with delayed sexual development // East European Science Journal. Vienna, 2019. № 11(51). P. 61–64.