DIFFERENTIAL DIAGNOSIS OF THE EROSIVE-ULCERATIVE FORM OF LICHEN PLANUS OF THE ORAL MUCOSA AND AUTOIMMUNE BULLOUS DERMATOSES

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Published: 2025-12-05
DOI: https://doi.org/10.66073/researchfocus.v4i11.1866
Keywords:
lichen planus, erosive-ulcerative form, pemphigus vulgaris, mucous membrane pemphigoid, direct immunofluorescence, serological markers, immunohistochemistry, differential diagnosis, oral mucosa

Main Article Content

Abdurasulova Jasmina Umarjonovna
1st year clinical resident of the Department of Dermatovenereology and Cosmetology of the Samarkand State Medical University. Uzbekistan, Samarkand, Amir Temur street, 18,
Narzikulov Rustam Mardonovich
Samarkand State Medical University. Uzbekistan, Samarkand, Amir Temur street, 18,

Abstract

This study presents a comparative clinical and laboratory analysis of patients with erosive-ulcerative lesions of the oral mucosa in order to develop criteria for the differential diagnosis of lichen planus, pemphigus vulgaris and mucous membrane pemphigoid. The analysis was carried out in three groups of patients. On the basis of clinical, morphological and immunological data, diagnostic algorithms were determined and the accuracy of the methods was assessed. The nature of the inflammatory infiltrate, the specificity of the immunofluorescence pattern and the spectrum of autoantibodies were analysed using statistical methods. In addition, the cumulative diagnostic accuracy of the comprehensive approach was calculated, which is an important practical indicator for clinicians.

Article Details

Issue

Vol. 4 No. 11 (2025): Research Focus International Scientific Journal. Volume 4, Issue 11 (2025)

Section

14.00.00 – Medical sciences
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This work is licensed under a Creative Commons Attribution 4.0 International License.

How to Cite

DIFFERENTIAL DIAGNOSIS OF THE EROSIVE-ULCERATIVE FORM OF LICHEN PLANUS OF THE ORAL MUCOSA AND AUTOIMMUNE BULLOUS DERMATOSES. (2025). Research Focus International Scientific Journal, 4(11), 272-279. https://doi.org/10.66073/researchfocus.v4i11.1866

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